Capstone I and II are related courses that consist of three components: learning strategies, critical analysis of scientific literature, and a thesis literature review. In Capstone I students develop strategies for learning including time management, study skills, organization, effective reading, testing skills, mindset, and motivation. Students learn how to interpret scientific literature and prepare scientific presentations. Students identify a topic related to the molecular mechanism of disease and develop a strategy for a literature review in consultation with the course director. Students apply the critical evaluation of scientific literature concepts to literature related to their thesis topics, and develop a comprehensive outline and annotated bibliography.