Gastrointestinal System provides a fundamental understanding of gastrointestinal basic science principles, and the application of this knowledge to gastrointestinal diseases. The five-week course covers normal features and pathological processes of the gastrointestinal system including physiology, pharmacology, anatomy, histology, pathology, mucosal immunology, nutrition, biochemistry, microbiology, developmental biology and neuroscience and relating these to pathologies of the gastrointestinal system. The course provides students with a comprehensive understanding of the diseases and disorders of the gastrointestinal system and its associated accessory organs to: (1) diagnose, effectively treat and manage gastrointestinal-related illnesses, (2) address patient issues and concerns regarding a gastrointestinal complaint and (3) understand the various gastrointestinal-related disorders associated with pediatric and geriatric patients. Clinical sciences and skills include discussion of the common causes of gastrointestinal diseases and disorders, collecting a relevant history based on an abdominal complaint and the appropriate evaluation and treatment of patients with common gastrointestinal abnormalities. Clinical cases are presented in a team-based learning format to provide reinforcement of basic science concepts as they relate to clinical applications.