Capstone I and II are related courses. The capstone courses consist of three components including learning strategies, critical analysis of scientific literature, and a capstone thesis literature review. In Capstone I, students develop strategies for learning including time management, study skills, organization, effective reading, testing skills, mindset, and motivation. Students learn how to interpret scientific literature and prepare scientific presentations. Students identify a topic related to the molecular mechanism of disease and develop a strategy for a literature review in consultation with the course directors. Students apply the critical evaluation of scientific literature concepts to literature related to their thesis topics, and develop a comprehensive outline and annotated bibliography. In Capstone II, students learn about scientific writing, and apply the skills learned in Capstone I to write a literature review based thesis. Students give an oral thesis presentation upon successful completion of Capstone II.